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Jeffrey Cummings Selected Research

NU-ICRF 505

5/2006Glucuronidation of SN-38 and NU/ICRF 505 in human colon cancer and adjacent normal colon.
1/2004Glucuronidation as a mechanism of intrinsic drug resistance in colon cancer cells: contribution of drug transport proteins.
2/2002Enhanced clearance of topoisomerase I inhibitors from human colon cancer cells by glucuronidation.

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Jeffrey Cummings Research Topics

Disease

71Alzheimer Disease (Alzheimer's Disease)
10/2022 - 05/2007
25Dementia (Dementias)
01/2022 - 04/2007
12Cognitive Dysfunction
01/2022 - 06/2007
9Parkinson Disease (Parkinson's Disease)
01/2022 - 07/2007
6Neurodegenerative Diseases (Neurodegenerative Disease)
01/2022 - 03/2013
6Psychotic Disorders (Schizoaffective Disorder)
01/2020 - 04/2007
6Neoplasms (Cancer)
05/2015 - 06/2000
6Colonic Neoplasms (Colon Cancer)
03/2008 - 02/2002
5Hallucinations (Hallucination)
01/2020 - 01/2010
5Disease Progression
01/2017 - 08/2011
4Vomiting
11/2007 - 05/2007
4Nausea
11/2007 - 05/2007
2Frontotemporal Dementia (Semantic Dementia)
01/2018 - 03/2010
2Atrophy
01/2015 - 01/2015
2Colorectal Neoplasms (Colorectal Cancer)
05/2006 - 02/2002
1Type 2 Diabetes Mellitus (MODY)
10/2022
1Sleep Wake Disorders
01/2020
1Inflammation (Inflammations)
01/2020
1Neurocognitive Disorders (Clerambault Syndrome)
01/2020
1Depressive Disorder (Melancholia)
01/2019
1Urinary Tract Infections (Urinary Tract Infection)
01/2018
1Neurobehavioral Manifestations
09/2017
1Prostatic Neoplasms (Prostate Cancer)
03/2014
1Protein Deficiency
03/2013
1Neuroinflammatory Diseases
03/2013
1Body Weight (Weight, Body)
08/2011
1Sleepiness
08/2011
1Diarrhea
08/2011
1Tremor (Tremors)
08/2011
1Multiple Sclerosis
11/2010
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
11/2010
1Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar)
03/2010
1Psychomotor Agitation (Akathisia)
08/2009
1Primary Progressive Aphasia
10/2008

Drug/Important Bio-Agent (IBA)

30Pharmaceutical PreparationsIBA
10/2022 - 12/2003
17Biomarkers (Surrogate Marker)IBA
01/2022 - 03/2008
9Amyloid (Amyloid Fibrils)IBA
01/2022 - 07/2011
9Donepezil (Aricept)FDA LinkGeneric
01/2022 - 01/2009
7Cholinesterase Inhibitors (Anticholinesterases)IBA
01/2018 - 07/2007
7Rivastigmine (Exelon)FDA LinkGeneric
09/2013 - 05/2007
5Cholinergic Agents (Cholinergics)IBA
01/2018 - 06/2007
4Proteins (Proteins, Gene)FDA Link
01/2021 - 12/2003
4Antipsychotic Agents (Antipsychotics)IBA
01/2019 - 06/2008
3Biological ProductsIBA
01/2021 - 01/2019
3pimavanserinIBA
01/2019 - 02/2014
3Capsules (Microcapsules)IBA
11/2007 - 05/2007
3NU-ICRF 505IBA
05/2006 - 02/2002
3Irinotecan (Camptosar)FDA LinkGeneric
05/2006 - 02/2002
3Topoisomerase I InhibitorsIBA
01/2004 - 02/2002
2Galantamine (Galanthamine)FDA LinkGeneric
01/2022 - 01/2017
2Risperidone (Risperdal Consta)FDA LinkGeneric
01/2022 - 01/2017
2Memantine (Namenda)FDA Link
01/2022 - 02/2011
2Glucose (Dextrose)FDA LinkGeneric
01/2021 - 01/2015
2Apolipoproteins E (ApoE)IBA
01/2021 - 08/2009
2Amyloid beta-PeptidesIBA
01/2015 - 01/2015
2N2- ((2S)- 2- (3,5- difluorophenyl)- 2- hydroxyethanoyl)- N1- ((7S)- 5- methyl- 6- oxo- 6,7- dihydro- 5H- dibenzo(b,d)azepin- 7- yl)- L- alaninamideIBA
01/2015 - 11/2010
2ProgranulinsIBA
03/2013 - 03/2010
2ApolipoproteinsIBA
08/2009 - 01/2008
2Uridine Diphosphate (UDP)IBA
01/2004 - 12/2003
1Insulin (Novolin)FDA Link
10/2022
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
10/2022
1Pioglitazone (Actos)FDA Link
10/2022
1SecretagoguesIBA
10/2022
1Glipizide (Glucotrol)FDA LinkGeneric
10/2022
1Sildenafil Citrate (Viagra)FDA Link
12/2021
1RNA (Ribonucleic Acid)IBA
10/2021
1aducanumabIBA
01/2021
1rasagiline (Azilect)FDA Link
01/2021
1Monoamine Oxidase (MAO)IBA
01/2021
1Complement System Proteins (Complement)IBA
01/2020
1Antidepressive Agents (Antidepressants)IBA
01/2019
1AcidsIBA
01/2019
1alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA
01/2019
1Oxytocin (Pitocin)FDA LinkGeneric
01/2018
1TabletsIBA
01/2018
15-HT2A Serotonin Receptor (5 HT2A Receptor)IBA
01/2018
16-fluoro-6-desoxyoxymorphone (FOXY)IBA
01/2018
1AZD3965IBA
05/2015
1Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link
01/2015
1Indicators and Reagents (Reagents)IBA
01/2015
1solanezumabIBA
01/2015
1Androgen Receptors (Androgen Receptor)IBA
03/2014
1AZD3514IBA
03/2014
1propionic acid (potassium propionate)IBA
05/2013
1N- ((2- (4'- (2- (methylsulfonyl)amino)ethyl)(1,1'- biphenyl)- 4- yl)propyl)- 2- propanesulfonamideIBA
05/2013
1tau Proteins (tau Protein)IBA
03/2013
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
03/2012
1Nootropic Agents (Nootropics)IBA
03/2012
1N-Methylaspartate (NMDA)IBA
03/2012
1Neurotransmitter Agents (Neurotransmitter)IBA
03/2012
1Valproic Acid (Depakote)FDA LinkGeneric
08/2011
1Excitatory Amino Acid AntagonistsIBA
02/2011
1Dextromethorphan (Racemethorphan)FDA LinkGeneric
11/2010
1Quinidine (Chinidin)FDA LinkGeneric
11/2010
1DNA-Binding Proteins (DNA Binding Protein)IBA
03/2010
1P-2 (P 2)IBA
03/2010

Therapy/Procedure

20Therapeutics
01/2022 - 03/2002
10Activities of Daily Living (ADL)
01/2022 - 11/2007
3Home Nursing (Nursing, Home)
01/2020 - 08/2009
2Drug Therapy (Chemotherapy)
05/2006 - 12/2003